Oral conditions and dysphagia in Japanese, community-dwelling middle- and older- aged adults, independent in daily living
The data collected from these participants included the following: number of teeth, occurrence of oral dryness, age, body mass index, serum albumin concentration, smoking, drinking and exercise habits, presence of diseases, such as diabetes mellitus and hypertension, and questions from the Mini-Mental State Examination.
Conclusion: This cross-sectional study demonstrated associations between oral conditions and dysphagia. Factors such as oral dryness and number of teeth may contribute to dysphagia more so than aging, lifestyle and comorbidity in community-dwelling adults over the age of 50.
The results of this study are representative of dysphagia in the community-dwelling population or in the more healthy population compared to those of previous studies. Using the volume-viscosity swallow test, Serra-Prat et al have examined the severity of dysphagia. They reported that the signs of dysphagia, impaired swallowing efficacy, impaired safety and aspiration were prevalent in 27.2%, 20.5%, 15.4% and 6.7% of the samples, respectively. However, they did not examine oral conditions. In this study, we did not clarify the type of dysphagia, and we examined oral conditions. We speculated that oral dryness and the number of teeth might have stronger associations with swallowing efficacy (impaired labial seal, oral or pharyngeal residue and piecemeal deglutition) rather than swallowing safety (changes in voice quality, cough or decrease in oxygen saturation), especially because participants in this study were considered to be health conscious. Therefore, for general population or healthy population, oral dryness and the number of teeth were more critical factors than other factors, such as nutritional status, lifestyle or previous medical history.
Når jeg læser denne artikel tænker jeg faktisk ret hurtigt, hvorfor teste serum albumin concentration, som der stod, men hvad handler det om? Og ja svaret giver jo mening, når vi taler dysfagi.
Men det med albumin siger mig et eller andet, med musklerne som jeg ikke lige kan huske hvad er.
Serum Albumin in Relation to Change in Muscle Mass, Muscle Strength, and Muscle Power in Older Men
Og nu begynder det at dæmre - inden for den del jeg kender bedst til, siden vi har det i familien
Biomarkers for Duchenne muscular dystrophy: myonecrosis, inflammation and oxidative stress
Simple diagram to indicate biomarkers in dystrophic muscle associated with the key events of myonecrosis. Some biomarkers are present only in muscle, whereas others can be detected in blood or urine (see Table 1 and text for details). Albumin ox., oxidised albumin; CK, creatine kinase; ROS, reactive oxygen species. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063669/
og noget med rhabdomyolyse, som vores gruppe skal være opmærksomme på, siden også bærere kan få det - det opstår, når muskelerne skades og lækker muskelenzymer der er skadelige for nyrene. Derfor vi skal være forsigtige ved motion, specielt overgørelse af motionen. Som igen er knyttet sammen med nyresvigt, der heller ikke er ukendt for vores gruppe.